OBJECTIVE To synthesize the presumable bone-targeting nonsteroidal anti-inflammatory agents.METHODS L-Asp6 was prepared by aspartic acid which was protected.

目的合成可能具有骨靶向性的非甾体抗炎药。

PASP-PEG block structure copolymer,comb shaped PASP-PEG block structure copolymer,aspartic acid and glycine,glutamic acid or propalanine copolymer are prepared.

还可以对聚天的侧链进行改性,引入烷基或烯烃基、反应活性高的基酯、磺基等功能性基团,使其得到更广泛的应用。

Aspartic acid An AMINO ACID formed by transamination, in which the amino group of dlutamic acid is transferred to oxaloacetic acid.

由转基作用形成的一种基，谷的基基团被转移到草酰乙中。

The tripeptide Arginyl-Glycyl-Aspartic acid (RGD) is a common cell recognition site of many adhesive proteins contained in extracellular matrices and in the blood .

RGD三肽（精酰-甘酰-天）序列是基质及血液中的许多粘附蛋白共有的识别位点。